ASHMAN PHENOMENON

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American Cancer Society Guidelines for the Early Detection of Cancer

American Cancer Society Guidelines for the Early Detection of Cancer

The American Cancer Society recommends these cancer screening guidelines for most adults. Screening tests are used to find cancer before a person has any symptoms.
Diet and Physical Activity: What’s the Cancer Connection?

Diet and Physical Activity: What’s the Cancer Connection?

How much do daily habits like diet and exercise affect your risk for cancer? Much more than you might think. Research has shown that poor diet and not being active are 2 key factors that can increase a person’s cancer risk. The good news is that you do something about this.

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Cancer treatment is improving, saving lives and extending survival for many people. Depending on various factors, treatment options may include surgery, radiation, immunotherapy, chemotherapy, hormone therapy, or targeted, local therapy, among others. These treatments might be used alone or in combination. Clinical trials evaluate the benefits of new therapies and broaden the options available to patients.

This section includes treatment trends for cancer sites for which there are available data trends and definitive treatment guidelines based on rigorous evidence of benefit to patients, including bladder, breast, colorectal, kidney, lung, ovarian, and prostate cancers.
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ASHMAN PHENOMENON Ashman phenomenon is an intraventricular conduction abnormality caused by a change in the heart rate. This is dependent on the effects

of rate on the electrophysiological properties of the heart and can be modulated by metabolic and electrolyte abnormalities and the effects of drugs. initial initial; background-repeat: initial initial;">The aberrant conduction depends on the relative refractory period of the components o the conduction system distal to the atrioventricular node. The refractory period depends on the heart rate. Action potential duration (ie, refractory period) changes with the R-R interval of the preceding cycle; shorter duration of action potential is associated with a short R-R interval and prolonged duration of action potential is associated with a long R-R interval. A longer cycle lengthens the ensuing refractory period, and, if a shorter cycle follows, the beat ending it is likely to be conducted with aberrancy. Aberrant conduction results when a supraventricular impulse reaches the His-Purkinje system while one of its branches is still in the relative or absolute refractory period. This results in slow or blocked conduction through this bundle branch and delayed depolarization through the ventricular muscles, causing a bundle-branch block configuration (ie, wide QRS complex) on the surface ECG, in the absence of bundle-branch pathology. A RBBB pattern is more common than a left bundle-branch block (LBBB) pattern because of the longer refractory period of the right bundle branch Epidemiology Frequency United States No geographic variations occur. Ashman phenomenon is related to the underlying pathology and is a common ECG finding in clinical practice. Mortality/Morbidity Ashman phenomenon is simply an electrocardiographic manifestation of the underlying condition; therefore, the morbidity and mortality is related to the underlying condition